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Non-competitive inhibition : ウィキペディア英語版 | Non-competitive inhibition
Non-competitive inhibition is a type of enzyme inhibition where the inhibitor reduces the activity of the enzyme and binds equally well to the enzyme whether or not it has already bound the substrate.〔(【引用サイトリンク】url=http://assay.nih.gov/assay/index.php/Types_of_Inhibition )〕 The inhibitor may bind to the enzyme whether or not the substrate has already been bound, but if it has a higher affinity for binding the enzyme in one state or the other, it is called a mixed inhibitor.〔 == Terminology == It is important to note that while all non-competitive inhibitors bind the enzyme at allosteric sites (i.e. locations other than its active site)—not all inhibitors that bind at allosteric sites are non-competitive inhibitors.〔 In fact, allosteric inhibitors may act as competitive, non-competitive, or uncompetitive inhibitors.〔 Many sources continue to conflate these two terms,〔(【引用サイトリンク】url=http://www.biology-online.org/biology-forum/about15032.html?hilit=Oscillates )〕〔(【引用サイトリンク】url=http://cti.itc.virginia.edu/~cmg/Demo/noncInh.html )〕 or state the definition of allosteric inhibition as the definition for non-competitive inhibition.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Non-competitive inhibition」の詳細全文を読む
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